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Formula: C28H26N4O4
The PKC inhibitor has no effect on vascular responses in normoglycemic and TR animals
It enhances the effectiveness of DNA-damaging anticancer drugs in transformed cells but not normal cells
3 and 1 mg/kg orally) ameliorated CIA in cynomolgus monkeys
LY364947 (25 mg/kg) increases p-Akt and decreases nuclear Foxo3a in leukaemia-initiating cells in CML-affected mice
CBL0137 Size:2mg solid Formula: C28H26N4O4CBL0137 (Curaxin 137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF B and activates p53 with EC50 of 0. 47 M and 0. 37 M, respectively. Product information CAS Number: 1197996 80 7 Molecular Weight: 336. 43 Formula: C21H24N2O2 Synonym: Curaxin 137 CBL C137 CBLC137 Chemical Name: 1,1' (9 (2 (isopropylamino)ethyl) 9H carbazole 3,6 diyl)bis(ethan 1 one) Smiles: