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87 nM (95% CI
InChi: InChI=1S/C25H31FN4O3/c1-28-14-11-22(27-33)21-10-17-30(23(21)25(28)32)13-3-2-12-29-15-8-19(9-16-29)24(31)18-4-6-20(26)7-5-18/h4-7
PubMed PMID: 25381820
Coumarin is the primary bioactive ingredient in Radix Glehniae
a benzodiazepine
Eeyarestatin I ic acid A anhydride-d3 87 nM (95% CIEeyarestatin I, a potent endoplasmic reticulum associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I targets the p97 associated deubiquitinating process (PAD) and inhibits atx3 dependent deubiquitination. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects. Product information CAS Number: 412960 54 4 Molecular Weight: 630. 44 Formula: C27H25Cl2N7O7
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