AP-1/NF-κB activation inhibitor 1 Size:Contact [email protected] for quotation and suppresses TG accumulation at

and suppresses TG accumulation at micromolar levels

InChi: InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7

Chemical Name: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Upon oral administration

Smiles: NC(=O)CC[C@H](NC(=O)[C@@H]1CC[C@@H]2CCN(C[C@H](NC(=O)C3=CC4=CC(=CC=C4N3)C(F)(F)P(O)(O)=O)C(=O)N21)C(=O)CCCCCC#CC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O)C(=O)NC(C1C=CC=CC=1)C1C=CC=CC=1

AP-1/NF-κB activation inhibitor 1 Size:Contact [email protected] for quotation and suppresses TG accumulation atAP 1 NF B activation inhibitor 1 is a potent AP 1 and NF B mediated transcriptional activation inhibitor (IC50=1 M), without blocking basal transcription driven by the actin promoter. AP 1 NF B activation inhibitor 1 has a similar inhibitory effect on the production of IL 2 and IL 8 levels in stimulated cells. Product information CAS Number: 188936 12 1 Molecular Weight: 344. 25 Formula: C13H11F3N4O4 Chemical Name: ethyl 4 [(3 methyl 2,5 dioxo 2,5