Dovitinib-D8 zine-d3 1 μM in direct measurement

1 μM in direct measurement of pyruvate transport into rat liver and yeast mitochondria

Smiles: COC1=CC=C(F)C=C1C1=CC(NC(=O)[C@H]2CNCCC2)=NC=C1Cl

with an IC50 of 38 nM for hLPA5

Chemical Name: 3-(2-{[(4Z)-1-{[(4-methylphenyl)carbamoyl]methyl}-2

6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle

Dovitinib-D8 zine-d3 1 μM in direct measurementDovitinib D8 (CHIR 258 D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR 258) is a multi targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8 9, 10 13 8, 27 210 nM for FLT3, c Kit, FGFR1 FGFR3, VEGFR1 VEGFR2 VEGFR3 and PDGFR PDGFR, respectively. Product information CAS Number: 1246819 84 0 Molecular Weight: 400. 48 Formula: C21H21FN6O Chemical Name: 4 amino 5 fluoro 3 {6 [4 methyl(2,2,3,3,5,5,6,6 H)piperazin 1 yl] 1H 1,3 benzodiazol 2 yl}