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4-dichlorophenyl)prop-2-en-1-yl]-1H-imidazole
24 hours) results in complete attenuation of IL-17A secretion in a concentration-dependent manner with an IC50 of 60 nM in HUT78 cells
LP533401 (250 mg/kg for 21 days) significantly reduced lung and blood 5-HT levels
7-²H₄)pyrazolo[1
Compound II-25
PXS-5120A 8784 4-dichlorophenyl)prop-2-en-1-yl]-1H-imidazolePXS 5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase like 2 3 (LOXL2 3) with anti fibrotic activity. PXS 5120A is >300 fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8. 4) over LOXL (pIC50 of 5. 8). Product information CAS Number: 2125955 70 4 Molecular Weight: 481. 97 Formula: C22H25ClFN3O4S Chemical Name: 1 [(2Z) 4 amino 2 fluorobut 2 en 1 yl] 3 [3 (dimethylsulfamoyl)phenyl] 2 methyl 1H indole 5 carboxylic acid
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