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1628838-42-5
This may lead to a reduction in TGFb-dependent proliferation of cancer cells
This compound exhibits selectivity for EBI2 over other receptors
339(1):228-37
treatment with enzastaurin and AR-A014418 decreases the mRNA levels and surface expression of CD44
SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 1628838-42-5SC 514, CAS No. 354812 17 2, is a selective and reversible inhibitor of IB kinase 2 (IKK2) that may target osteoclastogenesis. SC 514 dose dependently inhibits RANKL induced osteoclastogenesis and induced apoptosis and caspase 3 activation in RAW264. 7 cells. Targeting IKK by SC 514 may be a potential treatment for osteoclast related disorders such as osteoporosis and cancer induced bone loss. Product information CAS Number: 354812 17 2 Molecular
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