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Molecular Weight: 331
BRPF2 (100-fold) and BRPF3 (>1000-fold)
including initiation of protein synthesis
Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineagekinase domain-like protein
It strongly reduces the proliferation and cell viability of T-ALL cell lines
GNE-617 - CAS# 1362154-70-8 60100 Molecular Weight: 331GNE 617, CAS No. 1362154 70 8, is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC50 value of 5nM. Prolonged inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a strategy for targeting cancer metabolism. Product information CAS Number: 1362154 70 8 Molecular Weight: 427. 42 Formula: C21H15F2N3O3S Synonym: GNE 617 GNE 617 GNE617 Chemical Name: N (4 ((3,5 difluorophenyl)sulfonyl)benzyl)imidazo[1,2 a]pyridine 6