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Chemical Name: 3-(azepane-1-sulfonyl)-N-(3-bromophenyl)benzamide
KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures
α5β2γ2 and 0
6 days) treatment inhibits the growth of NCI-H929
This demonstrates our compounds cause ventralization of embryos consistent with increased BMP signaling activity
ORM-15341 erine metabolite O-desmethyl Mebeverine acid Chemical Name: 3-(azepane-1-sulfonyl)-N-(3-bromophenyl)benzamideORM 15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR HEK293 cells stably expressing full length hAR and an androgen responsive luciferase reporter gene construct. IC50 value: 38 nMTarget: androgen receptorin vitro: In competitive AR binding assays, the inhibition constant (Ki) values of ORM 15341 was 8 nM. ORM 15341 functions as a full antagonist for all tested mutant ARs ,
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