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is a selective Rev-Erbα/β agonist that increases wakefulness
Hirahara M
PubMed Central PMCID: PMC4421799
SB-743921 (1
4)diazepine
TW-37 Catalog No.:M7872-2 is a selective Rev-Erbα/β agonistTW 37 is a small molecule inhibitor of Bcl 2 family proteins, inhibited cell growth and induced apoptosis in pancreatic cancer. TW 37 induces cell growth inhibition and S phase cell cycle arrest, with regulation of several important cell cycle related genes like p27, p57, E2F 1, cdc25A, CDK4, cyclin A, cyclin D1, and cyclin E. The cell growth inhibition was accompanied by increased apoptosis with concomitant attenuation of Notch 1, Jagged 1, and its
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