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15(1):58-64
anti-inflammatory and insecticidal activities
InChi: InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H
PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively
Chemical Name: methyl (4S)-4-(3
4-phenyl-5-methyl-1, 2, 3-Thiadiazole ylpropionic acid 15(1):58-644 phenyl 5 methyl 1,2,3 Thiadiazole is a CYP2B4 and CYP2E1 inhibitor. Cytochrome P450 (CYP450) enzymes, a superfamily of oxidative catalysts, are important in the biosynthesis and metabolism of a wide range of endogenous molecules and the metabolism of xenobiotics. CYP2B4 can metabolize substituted amines, while CYP2E1 metabolizes various alcohols and halogenated alkenes. In vitro: 4 phenyl 5 methyl 1,2,3 Thiadiazole (PMT) was found to be slightly
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