StemRegenin1 (SR1) - HSC Expansion Molecule. CAS# 1227633-49-9 Catalog No.:M60001-2S CAS Number: 898562-94-2

CAS Number: 898562-94-2

Formula: C21H18F3NO3S2

Stock Solution Storage: Powder: 4oC 1 year

2009 Oct 13

StemRegenin1 (SR1) - HSC Expansion Molecule. CAS# 1227633-49-9 Catalog No.:M60001-2S CAS Number: 898562-94-2StemRegenin1 (SR1), CAS No. 1227633 49 9, is a selective, cell permeable antagonist of aryl hydrocarbon receptor. It can promote robust expansion and self renewal of human CD34+ peripheral blood and cord blood hematopoietic stem cells (HSCs, EC50 ~120 nM). SR1 expanded CD34+ cells from bone marrow of humans, monkeys and dogs, but not mice. Culture of HSCs with 1 M SR1 for 21 days led to a 50 fold increase in cells expressing CD34 and a 17 fold