The HLA-B*5701 allele has been associated with an increased risk of developing abacavir-induced DRESS syndrome in white patients.[2] Kashiwagi et al determined HLA-A*3101 is associated with an increased risk of DRESS syndrome to carbamazepine among Japanese patients.[20] Hung et al found a strong relationship between HLA-B*5801 and allopurinol inducing DRESS syndrome in Chinese population.[21] Reactivation of herpes viruses Systemic manifestations of DRESS are related to human herpes virus (HHV) reactivation and to host immune response against the virus
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This had the added benefit of securing the trim in place along the centerline, whereas the previous stitches were just on the sides of the trim