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Methyl-L-NIO (hydrochloride) 997elebactam 4-tetrahydroisoquinoline-3-carboxamide

SKU: 10111492583

4.8
USD121.00 USD160.00

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Description

4-tetrahydroisoquinoline-3-carboxamide

whose esters have important biological properties

4 ± 1

which are involved in tryptophan and nucleotide metabolism

Shigella fkxneri

Methyl-L-NIO (hydrochloride) 997elebactam 4-tetrahydroisoquinoline-3-carboxamideKi: 3. 0 M for nNOS; 10. 0 M for eNOS; 9. 5 M for iNOS Methyl L NIO is a competitive nitric oxide synthase (NOS) inhibitor. Nitric oxide synthase (NOS) catalyzes the NADPH and O2 dependent conversion of L arginine to nitric oxide (NO). Three isoforms, the neuronal (nNOS), endothelial, and inducible, have been identified. Since NO overproduction contributes to various pathophysiological conditions, NOS inhibitors are considered as potential therapeutic

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