CL2A Abd-7 Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18

Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18

3 nM for FGFR 1-4

Smiles: COC1=CC=CC(=C1)NC1=NC=NN2C=CC(CN3C[C@@H](O)[C@H](N)CC3)=C21

InChi: InChI=1S/C24H22F2N2O2/c25-19-4-1-3-17(13-19)22-5-2-12-28(22)15-16-6-9-20(10-7-16)30-23-11-8-18(24(27)29)14-21(23)26/h1

thereby inhibiting its activity as a protein that activates the ubiquitin-like protein UFM1 to UFMylate proteins

CL2A Abd-7 Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18CL2A is a claevable complicated PEG8 and triazole containing PABC peptide mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker. Product information CAS Number: 2616704 22 2 Molecular Weight: 1062. 21 Formula: C50H79N9O16 Chemical Name: N [(1 {26 [2 ({[(1S) 5 amino 1 {[4