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CAS Number: 16562-13-3
Smiles: CCN1C=C(CCC)C2N=C(NC(=O)C1=2)C1=CC(=CC=C1OCCC)S(=O)(=O)N1CCN(CCO)CC1
NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor
is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride
8)/b20-14+
NVP-TAE 226 - CAS# 761437-28-9 hlorobenzyl)-N2 N2-dimethyl-N1-(pyridin-2-yl)ethane-1 2-diamine hydrochloride CAS Number: 16562-13-3TAE226 is a novel and potent ATP competitive inhibitor of FAK and IGF IR with potential anticancer activity. TAE226 can block FAK and IGF IR signaling pathways. TAE226 inhibited the phosphorylation of FAK as well as the downstream effectors AKT, extracellular signal related kinase, and S6 ribosomal protein in multiple glioma cell lines. TAE226 induced a concentration dependent decrease in cellular proliferation with an associated G(2) cell cycle
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