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A significant reduction of PCSK9 promoter activity by Anacetrapib (ANA) is detected at 3 µM concentration (−22%
2 pM (-pIC50±SEM: 10
which may result in indirect tumoricidal effects
Tumor-bearing mice treated with 75 mg/kg of BMS-345541 shows effective inhibition of growth of SK-MEL-5
124:105-115
Ginsenoside Rk1 - CAS# 494753-69-4 12174 A significant reduction of PCSK9Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures[1]. Ginsenoside Rk1 has anti inflammatory effect, suppresses the activation of Jak2 Stat3 signaling pathway and NF B. Ginsenoside Rk1 has anti tumor effect, antiplatelet aggregation activities, anti insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and