Sp-cAMPS - CAS# 71774-13-5 AC RIPK degrader-6 Immunoproteasome subunit LMP7 deficiency and

Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation

InChi: InChI=1S/C13H12ClNOS2/c1-8-10-5-3-2-4-9(10)6-7-15(8)12-11(14)13(16)18-17-12/h2-5

Takahashi I

and orients tissue macrophages into an anti-inflammatory phenotype in ApoE2

Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents

Sp-cAMPS - CAS# 71774-13-5 AC RIPK degrader-6 Immunoproteasome subunit LMP7 deficiency andSp cAMPS, a cAMP analog, is potent activator of cAMP dependent PKA I and PKA II. Sp cAMPS is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47. 6 M. Sp cAMPS binds the PDE10 GAF domain with an EC50 of 40 M. Product information CAS Number: 71774 13 5 Molecular Weight: 345. 27 Formula: C10H12N5O5PS Chemical Name: (2S, 4aR, 6R, 7R, 7aS) 6 (6 amino 9H purin 9 yl) 7 hydroxy 2 sulfanyl hexahydro 2 furo[3, 2 d][1, 3,