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119(12):10358-10364
BLZ945 is a potent and selective CSF-1R kinase inhibitor
1 μm in a biochemical assay using an internally quenched fluorescent di-ubiquitin substrate
It catalyzes the palmitoylation of Wnt proteins
Significant efficacy can be achieved with GS-9876 doses that produces trough pSYK inhibition of <50%
Hydroxy-PEG2-(CH2)2-Boc ladesine calcium salt 119(12):10358-10364Hydroxy PEG2 (CH2)2 Boc is a uncleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Hydroxy PEG2 (CH2)2 Boc is extracted from patent WO2004008101A2 (compound 196). Hydroxy PEG2 (CH2)2 Boc is also a PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 133803 81 3 Molecular Weight: 234. 29 Formula: C11H22O5 Chemical Name: tert butyl 3 [2 (2 hydroxyethoxy)ethoxy]propanoate Smiles:
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