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05 μM (p=0
and the combination of SMI-4a and a mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor was highly synergistic in killing pre-T-LBL cells
it is more 5-fold selective for MT1 over MT2
except for the 1
a thienopyridine and prodrug
BIBB 515 rgine hydrochloride 05 μM (p=0BIBB 515 is a potent, selective and orally active 2,3 oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0. 2 0. 5 mg kg and 0. 36 33. 3 mg kg in rats and mice (1 5 hours), respectively. BIBB 515 exerts lipid lowering effect mainly by inhibiting the production of low density lipoprotein (LDL). Product information CAS Number: 156635 05 1 Molecular Weight: 380. 87 Formula: C22H21ClN2O2 Chemical Name: 1 (4 chlorobenzoyl) 4 {[4 (4,5 dihydro 1,3
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