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SGI-110 Size:Solid 10 mg CAS Number: 2752-65-0

SKU: 21138090273

4.1
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Description

CAS Number: 2752-65-0

Formula: C18H20N4

KAN 0438757

Smiles: CCN(CCCC(O)=O)C(C)CC1C=CC(=CC=1)OC

It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage

SGI-110 Size:Solid 10 mg CAS Number: 2752-65-0Guadecitabine, aslo known as SGI 110, is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and incorporation into DNA, SGI 110 inhibits DNA methyltransferase, thereby causing genome wide and non specific hypomethylation and inducing cell cycle arrest at S phase. This agent is resistant to cytidine deaminase, hence may

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