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Abaloparatide TFA o-PEG3-alcohol 24 h) stimulates erythropoietin (Epo)

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Description

24 h) stimulates erythropoietin (Epo) secretion by PHD2 inhibition in Hep3B cells

InChiKey: JOKVJNCYOSFDGC-LJAQVGFWSA-N

The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease

Manning Fox JE

3 μM against the p53/mDM2 pair

Abaloparatide TFA o-PEG3-alcohol 24 h) stimulates erythropoietin (Epo)Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue selected to be a potent and selective activator of the PTHR1 signaling pathway. Abaloparatide TFA enhances Gs cAMP signaling (EC50 of 0. 3 nM) and arrestin recruitment (EC50 of 0. 9 nM) in MC3T3 E1 osteoblast cells. Product information Chemical Name: Ala Val Ser Glu His Gln Leu Leu His Asp Lys Gly Lys Ser Ile Gln Asp Leu Arg Arg Arg Glu Leu Leu Glu Lys Leu Leu {Aib}

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