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The IC50 for AMG8379 inhibition of C-fiber spiking based on the level of firing in NaV1
InChi: InChI=1S/C32H33ClN8O2/c1-4-28(42)36-26-10-5-6-11-27(26)37-30-24(31(43)38-29-21(2)8-7-9-25(29)33)20-34-32(39-30)35-22-12-14-23(15-13-22)41-18-16-40(3)17-19-41/h4-15
Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1O
Illingworth NA
02 mM) DMSO : ≥ 125 mg/mL (483
CS-722 Free base Catalog No.:M16327-C The IC50 for AMG8379 inhibitionCS 722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex. CS 722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents. Product information CAS Number: 749179 13 3 Molecular Weight: 338. 79 Formula: C16H19ClN2O4 Chemical Name: 4
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