SBI-0640756 idotoxin TFA Smiles: CNS(=O)(=O)C1=CC=C(F)C(C2=C3C=CC(N3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3CCC(N=3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3=CC=C(N3)C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)=C3CCC2=N3)=C1F

Smiles: CNS(=O)(=O)C1=CC=C(F)C(C2=C3C=CC(N3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3CCC(N=3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3=CC=C(N3)C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)=C3CCC2=N3)=C1F

33-19-17(28)16(27)15(26)14(9-24)32-19)22(12

Chrysophanic acid (Chrysophanol) preferentially blocks proliferation in SNU-C5 cells but not in other cell lines (HT7

Hodivala-Dilke K

ML327-pretreated cells demonstrates reduced proliferative potential in both tetrazolium-based (p<0

SBI-0640756 idotoxin TFA Smiles: CNS(=O)(=O)C1=CC=C(F)C(C2=C3C=CC(N3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3CCC(N=3)=C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)C3=CC=C(N3)C(C3=C(F)C(=CC=C3F)S(=O)(=O)NC)=C3CCC2=N3)=C1FSBI 0640756 (SBI 756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex. Product information CAS Number: 1821280 29 8 Molecular Weight: 404. 82 Formula: C23H14ClFN2O2 Chemical Name: 6 chloro 3 [(2E) 3 (5 fluoropyridin 3 yl)prop 2 enoyl] 4 phenyl 1,2 dihydroquinolin 2 one Smiles: O=C1NC2C=CC(Cl)=CC=2C(=C1C(=O) C=C C1C=NC=C(F)C=1)C1C=CC=CC=1 InChiKey: VVWGPQZBDQVQRC RMKNXTFCSA N InChi: InChI=1S C23H14ClFN2O2 c24 16 7 8 19 18(11 16)21(15 4 2 1 3 5