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2BrH/c1-33(2)31-17-21-35(22-18-31)25-29-13-9-27(10-14-29)7-5-6-8-28-11-15-30(16-12-28)26-36-23-19-32(20-24-36)34(3)4
thereby prolonging repolarization
InChiKey: MFSSHRCJKRDIOL-UHFFFAOYSA-N
7 inhibitor
Ethacrynic acid decreases expression of proinflammatory intestinal wall cytokines and ameliorates gastrointestinal stasis in murine postoperative ileus
Raloxifene 4'-glucuronide 11377 2BrH/c1-33(2)31-17-21-35(22-18-31)25-29-13-9-27(10-14-29)7-5-6-8-28-11-15-30(16-12-28)26-36-23-19-32(20-24-36)34(3)4Raloxifene 4' glucuronide is a primary metabolite of Raloxifene. Raloxifene 4' glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4' glucuronide binds to estrogen receptor with an IC50 of 370 M. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product
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