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Valganciclovir Hydrochloride uhzin CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3C

SKU: 24119005986

4.4
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Description

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3C

552292-08-7

Molecular Weight: 291

The selectivity of protein kinase inhibitors: a further update

7a-hexahydrocyclopenta[c]pyran-4-carboxylate

Valganciclovir Hydrochloride uhzin CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3CValganciclovir is an L valyl ester (prodrug) of ganciclovir that exists as a mixture of two diastereomers. After oral administration, both diastereomers are rapidly converted to ganciclovir by intestinal and hepatic esterases. Ganciclovir is a synthetic analogue of 2' deoxyguanosine, which inhibits replication of human CMV in cell culture and in vivo. The reported EC50 values of ganciclovir that inhibit human CMV replication in cell culture

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