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8-tetraene-14
10-trimethyl-4-oxo-4H
Chemical Name: {4-[(pyridin-2-yl)[4-(sulfooxy)phenyl]methyl]phenyl}oxidanesulfonic acid sodium
Formula: C9H13N2O9P
10 µM KGN in 4 µl of saline was intra-articularly (IA) delivered into mice on days 7 and 21 in the collagenase VII–induced model and the acute surgical model
Cl-amidine hydrochloride RP 8-tetraene-14Cl amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0. 8 M, 6. 2 M and 5. 9 M for PAD1, PAD3, and PAD4, respectively. Cl amidine hydrochloride induces apoptosis in cancer cells. Cl amidine hydrochloride induces microRNA (miR) 16 (miRNA 16, microRNA 16) expression and causes cell cycle arrest. Cl Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation,