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29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33
InChiKey: NMDYYWFGPIMTKO-KLCPSUAYSA-N
37-trimethoxy-12
also known as HM781-36B and NOV120101
Formula: C15H22N2O4
Mutant IDH1-IN-2 ecyl sulfate D25 29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33Mutant IDH1 IN 2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS MS biochemical assay, IC50 of 16. 6 nM in Fluorescence biochemical assay. Target: Mutant IDH1Mutant IDH1 IN 2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell proliferation disorders, such as cancer. More bioactivity information in Patent WO
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