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Saracatinib
Williams VC
OTS964 hydrochloride (intravenously
InChiKey: CMSMOCZEIVJLDB-UHFFFAOYSA-N
Formula: C21H23N5O3S
SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg SaracatinibSU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet derived growth factor receptors (PDGFR), KIT, and fms like tyrosine kinase 3 (FLT 3) (1). SU14813 was developed as a next generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity