AACOCF3 Catalog No.:M16172-C Formula: C18H23ClN4O4

Formula: C18H23ClN4O4

134(2):934-43

InChi: InChI=1S/C17H25NO9/c1-2-5-22-6-7-23-8-9-24-10-11-25-12-13-26-14-17(21)27-18-15(19)3-4-16(18)20/h1H

FES and SAMSN1 genes in Kasumi-1 cells

Smiles: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)CC1C=CC(O)=CC=1)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

AACOCF3 Catalog No.:M16172-C Formula: C18H23ClN4O4AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85 kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12 hydroxyeicosatetraenoic acid by calcium ionophore challenged platelets. AACOCF3 inhibits glucose induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the