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Heclin does not block E2 binding but causes a conformational change that results in oxidation of the active site Cys
and active in six different assays that represent distinct neurotoxicity pathways related to aging and neurodegenerative diseases
LY2886721 is under clinical study
InChiKey: SLUINPGXGFUMLL-UHFFFAOYSA-N
1222800-79-4
Ki-16425 - CAS# 355025-24-0 pound Library of Histone Demethylase Heclin does not block E2Ki16425, CAS No. 355025 24 0, is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0. 34 M, 6. 5 M and 0. 93 M, respectively, shows no activity at LPA4, LPA5, LPA6. IC50 value: 0. 3 6. 5 0. 93 uM(Ki, LPA1 2 3) Target: LPA1 2 3 Product information CAS Number: 355025 24 0 Molecular Weight: 474. 96 Formula: C23H23ClN2O5S Chemical Name: 3 ((4 (4 (((1 (2 chlorophenyl)ethoxy)carbonyl)amino) 3 methylisoxazol 5
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