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PubMed PMID: 17098432
1 μM or lower
This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response
Glycogen synthase kinase 3 (GSK3) inhibitor
On day 1 of the experiment
N-Ethyl-3, 3, 3-trifluoro-N-methylpropanamide-PEG2-Br GR-(NMe)k) TFA PubMed PMID: 17098432N Ethyl 333 trifluoro N methylpropanamide PEG2 Br is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information Molecular Weight: 336. 15 Formula: C10H17BrF3NO3 Chemical Name: N {2 [2 (2 bromoethoxy)ethoxy]ethyl} 3,3,3 trifluoro N methylpropanamide Smiles: CN(CCOCCOCCBr)C(=O)CC(F)(F)F InChiKey: IFJWNKDDGDBITI UHFFFAOYSA N InChi: InChI=1S C10H17BrF3NO3 c1 15(9(16)8 10(12,13)14)3 5 18 7 6 17 4 2 11 h2 8H2,1H3 Technical