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4-thiadiazol-3-yl)methyl]sulfanyl}phosphonothioate
DO3A tert-butyl
(2004) J Cardiovasc Pharmacol
IC50 values for the non-AGC kinases CHK2 and Aurora B are both greater than 800 nM
231(2):180-4
(R)-Baclofen n hydrochloride 4-thiadiazol-3-yl)methyl]sulfanyl}phosphonothioateArbaclofen, also known as (R) Baclofen, D Baclofen and STX209, is a selective GABA B agonist and is hypothesized to modulate the balance of excitatory to inhibitory neurotransmission, and has shown preliminary evidence of benefit in fragile X syndrome. STX209 may be a potentially effective therapy to treat the core symptoms of FXS. Autism spectrum disorder (ASD) is a behaviorally defined disorder which has increased in prevalence over the last two
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