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Formula: C13H9ClN2O3
3 μM) but not p110α/p85α PI3K (IC50>100 μM)
Swearingen D
LY2784544 significantly inhibits STAT5 phosphorylation in JAK2-V617F Ba/F3 xenografts with a Threshold Effective Dose 50 (TED50) of 12
in liver microsomes of rats
MGL-3196 - CAS# 920509-32-6 PTO-253 Formula: C13H9ClN2O3MGL 3196, CAS No. 920509 32 6, also known as Resmetirom, is a potent and highly selective thyroid hormone receptor agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor (THR ) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor (THR ). Product information CAS Number: