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It inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH)
Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle
EKB-569 irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1
5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
Wogonin suppresses the LPS enhanced invasiveness of MDA MB 231 breast cancer cells by inhibiting the 5 LO/BLT2 cascade
Thalidomide D4 - CAS# 1219177-18-0 R40 Activator 1 It inhibits hypoxia-inducible factor αThalidomide D4 is a deuterium labeled Thalidomide. Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin 4 E3 ubiquitin ligase complex CUL4 RBX1 DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti inflammatory and anti angiogenic cancer properties. Product information CAS Number: 1219177 18 0 Molecular Weight: 262. 25 Formula: C13H10N2O4 Chemical Name: 2 (2, 6 dioxopiperidin 3 yl) 2, 3 dihydro(H) 1H
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