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Danirixin Size:10mg This isozyme preferentially utilizes arachidonate

SKU: 48930079232

4.6
USD52.00 USD94.00

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Description

This isozyme preferentially utilizes arachidonate as substrate

Flexible instrument compatibility: Compatible with multiple real-time PCR platforms (instructions include detector/channel setup and reference dye settings)

Graduated tips

Available in single-channel and multichannel configurations

Storage Conditions and Validity Period

Danirixin Size:10mg This isozyme preferentially utilizes arachidonateDescription Danirixin (GSK1325756) is an orally active, selective CXC chemokine receptor 2 (CXCR2) antagonist with 78 fold lower affinity toward CXCR1 (CXCR2 CXCR1 IC50 = 12. 5 977 nM by competitive binding against 0. 225 nM [125I] CXCL8). Danirixin blocks agonist induced neutrophil CD11b expression in vitro (IC50 = 420 890 nM against induction by 10 nM human CXCL1 rat CXCL2 using rat human whole blood) and prevents lung neutrophils influx in rats in

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