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2018 Jul 16
which markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells
InChiKey: SWMDAPWAQQTBOG-UHFFFAOYSA-N
dBET1-mediated targeted degradation of BET proteins robustly dampens pro-inflammatory responses in LPS-stimulated microglia
The combination had greater efficacy than either reparixin or docetaxel alone
PF-562271 besylate - CAS# 939791-38-5 aminophen metabolite 3-hydroxy-acetaminophen 2018 Jul 16PF 562271 Besylate, also known as PF 562,271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF 562271 benzesulfonate is also called PF 562271
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