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induces apoptosis in primary AML marrow blasts but not in normal myeloblasts
cleaved-caspase3
1 mg/kg (p
Western blotting analysis shows that Afuresertib increases the expression of p21WAF1/CIP1 and decreases the phosphorylation of Akt substrates
Smiles: CCOC(=O)[C@H](NC(=O)[C@H](CSCC1C=CC=CC=1)NC(=O)CC[C@H](N)C(=O)OCC)C1C=CC=CC=1
(S)-(+)-Modafinic acid - CAS# 112111-44-1 0312 induces apoptosis in primary AMLModafinil acid, (+) is a bioactive chemical. Product information CAS Number: 112111 44 1 Molecular Weight: 274. 33 Formula: C15H14O3S Chemical Name: 2 [(S) diphenylmethanesulfinyl]acetic acid Smiles: OC(=O)C[S@](=O)C(C1C=CC=CC=1)C1C=CC=CC=1 InChiKey: QARQPIWTMBRJFX IBGZPJMESA N InChi: InChI=1S C15H14O3S c16 14(17)11 19(18)15(12 7 3 1 4 8 12)13 9 5 2 6 10 13 h1 10,15H,11H2,(H,16,17) t19 m0 s1 Technical Data Appearance: Solid Power Purity: 98% (or refer
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