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DM1-SMCC - CAS# 1228105-51-8 11440 InChi: InChI=1S/C31H39N7O2/c1-6-7-23-14-21(4)35-31(40)26(23)18-33-30(39)25-15-24(16-28-27(25)19-34-38(28)20(2)3)22-8-9-32-29(17-22)37-12-10-36(5)11-13-37/h8-9

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Description

InChi: InChI=1S/C31H39N7O2/c1-6-7-23-14-21(4)35-31(40)26(23)18-33-30(39)25-15-24(16-28-27(25)19-34-38(28)20(2)3)22-8-9-32-29(17-22)37-12-10-36(5)11-13-37/h8-9

stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB)

Other Angiotensin II actions include induction of growth

3]thiazolo[4

Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment

DM1-SMCC - CAS# 1228105-51-8 11440 InChi: InChI=1S/C31H39N7O2/c1-6-7-23-14-21(4)35-31(40)26(23)18-33-30(39)25-15-24(16-28-27(25)19-34-38(28)20(2)3)22-8-9-32-29(17-22)37-12-10-36(5)11-13-37/h8-9DM1 SMCC (SMCC DM1) is an antibody drug conjugate (ADC) linker consists of a potent microtubule disrupting agent DM1 and a linker SMCC. Product information CAS Number: 1228105 51 8 Molecular Weight: 1072. 61 Formula: C51H66ClN5O16S Chemical Name: 2,5 dioxopyrrolidin 1 yl 4 ({3 [(2 {[(2S) 1 {[(1S,2R,3S,5S,6S,20R,21S) 11 chloro 21 hydroxy 12,20 dimethoxy 2,5,9,16 tetramethyl 8,23 dioxo 4,24 dioxa 9,22 diazatetracyclo[19. 3. 1. 1,. 0,]hexacosa

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