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BETP can enhance cAMP efficacy of GLP-1(9-36)NH2 at GLP-1R but not intracellular calcium mobilization
3-benzoxadiazol-7-amine
While cAMP competes with 8-NBD-cAMP binding with an IC50 of 39 µM
but not activity of other SCF complexes
TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis
VU-0357121 - CAS# 433967-28-3 size:10mg solid BETP can enhance cAMP efficacyVU 0357121, CAS No. 433967 28 3, is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that VU 0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site. Product information CAS Number: 433967 28 3 Molecular Weight: 305. 32 Formula: C17H17F2NO2 Synonym: VU 0357121 VU 0357121 VU0357121 Chemical Name: 4
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