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HZ52 inhibited 5-LO with an IC50 of 9 μM
Smiles: CCN(CC)C(=O)C1C=CC(=CC=1)NC1N=C2N=CNC2=C(N=1)OCC1CCCCC1
CAS Number: 383199-88-0
especially after microbial fermentation
Formula: C15H16O3
H3B-5942 )-(+)-Rolipram HZ52 inhibited 5-LO with anH3B 5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild type and mutant ER by targeting Cys530, with Kis of 1 nM and 0. 41 nM, respectively. H3B 5942 reduces ER target gene GREB1, shows potent antitumor activity both in multiple cell lines or animals bearing ERWT or ER mutations. Product information CAS Number: 2052128 15 9 Molecular Weight: 494. 63 Formula: C31H34N4O2 Chemical Name: (2E) 4
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