Paris saponin VII ole A PETCM promotes Apaf-1 oligomerization and

PETCM promotes Apaf-1 oligomerization and induces cell apoptosis in HeLa cells

InChiKey: NWIUTZDMDHAVTP-UHFFFAOYSA-N

with potential as a treatment for ADHD

InChiKey: GSQOBTOAOGXIFL-LFIBNONCSA-N

1-5H3/b22-12+/t14-

Paris saponin VII ole A PETCM promotes Apaf-1 oligomerization andParis saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim. Paris saponin VII induced apoptosis in K562 ADR cells is associated with Akt MAPK and the inhibition of P gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl 2, caspase 9,