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Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in androgen-responsive prostate cancer cell LNCaP
An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression
PubMed PMID: 24131248
InChi: InChI=1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31
enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats
WIN-55212-2 mesylate - CAS# 131543-23-2 031 Pleiotropic effects of the sirtuinWIN 55212 2 mesylate, CAS No. 131543 23 2, is a CB1 agonist (cannabinoid receptor agonist). WIN 55212 2 impairs contextual fear conditioning through the activation of CB1 cannabinoid receptors. Win 55212 2 attenuates leukocyte endothelial interactions in an experimental autoimmune encephalomyelitis model. WIN 55212 2 inhibits neurogenic inflammations in airway tissues. Product information CAS Number: 131543 23 2 Molecular Weight: 522. 61 Formula:
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