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ADX-47273 increased (9-fold) the response to threshold concentration of glutamate (50 nM) in fluorometric Ca(2+) assays (EC(50) = 170 nM) in human embryonic kidney 293 cells expressing rat mGlu5
4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazide
InChi: InChI=1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H
212141-51-0 (Vatalanib hydrochloride)
3-d]imidazol-3-ium bromide
Scopine Hydrochloride 0185 ADX-47273 increased (9-fold) the responseScopine HCl is a metabolite of the muscarinic antagonist scopolamine. Scopine binds to muscarinic acetylcholine receptors and is selective for muscarinic acetylcholine receptors over nicotinic acetylcholine receptors. It reduces hyperphagia induced by the antipsychotics loxapine and chlorpromazine. When conjugated to chlorambucil, scopine improves the blood brain barrier permeability of chlorambucil. Product information CAS Number: 85700 55 6