TAI-1 470uman PD-L1 inhibitor V TFA InChi: InChI=1S/C46H54ClFN8O8/c1-62-38-28-35-32(43(51-29-50-35)52-30-12-13-34(48)33(47)26-30)27-39(38)64-25-9-18-54-20-22-55(23-21-54)19-16-40(57)49-17-6-4-2-3-5-7-24-63-37-11-8-10-31-42(37)46(61)56(45(31)60)36-14-15-41(58)53-44(36)59/h8

InChi: InChI=1S/C46H54ClFN8O8/c1-62-38-28-35-32(43(51-29-50-35)52-30-12-13-34(48)33(47)26-30)27-39(38)64-25-9-18-54-20-22-55(23-21-54)19-16-40(57)49-17-6-4-2-3-5-7-24-63-37-11-8-10-31-42(37)46(61)56(45(31)60)36-14-15-41(58)53-44(36)59/h8

23-13-19-33-29(37)25-15-7-8-16-26(25)30(33)38)21-11-5-6-12-22-36(3

2HI/c1-4-31(3

28)/t15-/m0/s1

InChi: InChI=1S/C27H28F2N6O/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20/h1-3

TAI-1 470uman PD-L1 inhibitor V TFA InChi: InChI=1S/C46H54ClFN8O8/c1-62-38-28-35-32(43(51-29-50-35)52-30-12-13-34(48)33(47)26-30)27-39(38)64-25-9-18-54-20-22-55(23-21-54)19-16-40(57)49-17-6-4-2-3-5-7-24-63-37-11-8-10-31-42(37)46(61)56(45(31)60)36-14-15-41(58)53-44(36)59/h8TAI 1, an orally active anticancer agent, is a highly potent first in class Hec1 inhibitor, with a GI50 of 13. 48 nM in K562 cells. Product information CAS Number: 1334921 03 7 Molecular Weight: 429. 53 Formula: C25H23N3O2S Chemical Name: 4 [4 (4 methoxyphenoxy) 2,6 dimethylphenyl] N [1 (pyridin 4 yl)ethenyl] 1,3 thiazol 2 amine Smiles: COC1C=CC(=CC=1)OC1=CC(C)=C(C2=CSC(NC(=C)C3C=CN=CC=3)=N2)C(C)=C1 InChiKey: RIHDNDGYTTXMDR UHFFFAOYSA N InChi: