GSK-3787 - CAS# 188591-46-0 60167 Smiles: CC(=O)C1=CC(=C(SC2=CC=C(F)C=C2F)S1)[N+]([O-])=O

Smiles: CC(=O)C1=CC(=C(SC2=CC=C(F)C=C2F)S1)[N+]([O-])=O

Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering

potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC50 for LRRK2-wild-type ~20

3-d]imidazol-3-ium bromide

CC(=O)C1C(=O)N(C2CCCC2)C2=NC(NC3=CC=C(C=N3)N3CCNCC3)=NC=C2C=1C

GSK-3787 - CAS# 188591-46-0 60167 Smiles: CC(=O)C1=CC(=C(SC2=CC=C(F)C=C2F)S1)[N+]([O-])=OGSK 3787, CAS No. 188591 46 0, is a selective and irreversible peroxisome proliferator activated receptor delta (PPARdelta) antagonist with good pharmacokinetic properties. GSK3787 can antagonize PPARbeta delta in vivo, thus providing a new strategy to delineate the functional role of a receptor with great potential as a therapeutic target for the treatment and prevention of disease. Product information CAS Number: 188591 46 0 Molecular Weight: 392.