ADX 10059 hydrochloride Size:Contact [email protected] for quotation 3)8-13(23)20-14-11(18)6-10(7-12(14)19)15(24)21-16-22(4-5-30-16)9-28-29(25

3)8-13(23)20-14-11(18)6-10(7-12(14)19)15(24)21-16-22(4-5-30-16)9-28-29(25

2015 Dec 21

277(1):114-20

CAS Number: 1219409-06-9

Molecular Weight: 4230

ADX 10059 hydrochloride Size:Contact [email protected] for quotation 3)8-13(23)20-14-11(18)6-10(7-12(14)19)15(24)21-16-22(4-5-30-16)9-28-29(25ADX 10059 hydrochloride is a potent and selective negative allosteric modulator of mGlu5 receptor with IC50 value of 17. 1 nM . Metabotropic glutamate receptor 5 (mGlu5 receptor) is a G protein coupled receptor and is a receptor for glutamate, which is a primary neurotransmitter involved in signaling in the central nervous system . ADX 10059 hydrochloride is a potent and selective mGlu5 receptor negative allosteric modulator. In patients with