Slime Against Humanity joins the illustrious club of Can Run More Than One of This Card In Commander along with Relentless Rats, Shadowborn Apostle and Persistent Petitioners, among others
Cracking packs for Chase cards, however, is a gamble
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Each of the four Commander Decks comes with a scheme deck (including some schemes new with this release) that you can use to strike fear into the hearts of your opponents
If it gave ALL your creatures indestructible, then MAYBE it might see play in EDH
This is far too specific to include in something like a Commander deck, and theres infinitely better sideboard tech out there for other formats
