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Formula: C84H109ClN18O19
Smiles: CN1C(C2C=CC(Cl)=CC=2)S(=O)(=O)CCC1=O
FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1
N'-(piperazine-1
is a Hedgehog agonist
JSH-23 - CAS# 749886-87-1 Catalog No.:M9452-10 Formula: C84H109ClN18O19JSH 23 is a nuclear factor kappa B (NF B) nuclear translocation inhibitor. JSH 23 inhibits LPS and cytokine induced nuclear translocation of the p65 subunit of NF kB as analyzed by EMSA and western blot. JSH 23 treatment significantly reversed the nerve conduction and nerve blood flow deficits seen in diabetic animals. Reduction in mechanical pain threshold was also partially corrected by the treatment. Protein expression studies showed that nuclear