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Cathepsin S inhibitor 801653 dihydrochloride 51(11):669-75

SKU: 5015357607

4.6
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Description

51(11):669-75

Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells

are significantly lower than the IC50 values calculated for cells cultured in the presence of PAI-039 under attached condition

Rho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases or conditions associated with excessive cell proliferation

4-dichlorophenoxy)methyl]-2-fluoro-N-methanesulfonylbenzamide

Cathepsin S inhibitor 801653 dihydrochloride 51(11):669-75LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. Product information CAS Number: 1373215 15 6 Molecular Weight: 484. 52 Formula: C25H29FN4O5 Chemical Name: (3R,4S) 4

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