![AZ 12080282 dihydrochloride 2653 Smiles: CCCCCCC(C)(C)C1=CC(OC)=C([C@H]2C=C(CO)[C@H]3C[C@@H]2C3(C)C)C(=C1)OC](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M22820_1635330716.gif?v=1635330717)
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Smiles: CCCCCCC(C)(C)C1=CC(OC)=C([C@H]2C=C(CO)[C@H]3C[C@@H]2C3(C)C)C(=C1)OC
1007/s12032-013-0546-3
Coaxil sodium salt
6(11):1445-57
Cadazolid levels persists at 50-100-fold supra-MIC for 14 days post-dosing
AZ 12080282 dihydrochloride 2653 Smiles: CCCCCCC(C)(C)C1=CC(OC)=C([C@H]2C=C(CO)[C@H]3C[C@@H]2C3(C)C)C(=C1)OCAZ 12080282 dihydrochloride is a selective inhibitor of Hh with IC50 value <0. 012 M . It is also reported that AZ 12080282 also has a selective inhibition to p38 with low nanomolar potency . Hedgehog (Hh) signaling plays an important role in a wide variety of developmental processes, including larval body segment development and adult appendages formation. Abnormal activation of Hh pathway may lead to developmental disease by transforming adult stem
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